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Smaller doses of GLP-1 RAs may not benefit those with severe metabolic dysfunction or those needing substantial weight loss

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For patients with Hashimoto's disease who also have obesity or type 2 diabetes, a comprehensive treatment approach addressing all conditions is appropriate

Tirzepatide is a dual GIP/GLP-1 receptor agonist (the active ingredient in Zepbound and Mounjaro)

The 0.6 mg dose (20 units) typically represents the third or fourth escalation step in standard titration schedules