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doi: 10.1016/j.brainres.2010.09.071 52 CarusoSGrilloCAgnelloCMaiolinoLIntelisanoGSerraA

Despite these limitations, current guidance recommends a diet that leads to a caloric deficit

Additionally, in patients with type 2 diabetes and atherosclerotic cardiovascular disease or chronic kidney disease, a GLP-1 receptor agonist or sodiumglucose cotransporter 2 (SGLT2) inhibitor with proven cardiovascular benefit is recommended as a first-line therapy for the reduction of cardiovascular risk (46)