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Treatment of human and mouse small intestine organoid models with SCFAs increases the number of GLP-1-producing cells twofold 284 , and SCFA infusion activates colonic EECs to increase GLP-1 release in mice 281

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Volpe S, Lisco G, Fanelli M, Racaniello D, Colaianni V, Triggiani D, Donghia R, Crudele L, Rinaldi R, Sabb C