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moderate-certainty evidence), and 36 months (MD 4.10, 95% CI 1.40 to 6.79

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In HF with preserved ejection fraction and mildly reduced ejection fraction, semaglutide improved symptoms, physical function, natriuretic peptide levels, echocardiographic parameters, and HF hospitalizations, as shown in the STEP-HFpEF program and a pooled analysis of trials

One common theme is improved portion control at meals, leading to effortless calorie reduction

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