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Regarding GLP-1 expression, SCFA and bile acids are the best-studied links between microbiota and gut hormone secretion

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Malik S, Loganathan P, Khan K, Mohan BP, Adler DG

The 5- and 10-year survival probabilities in this matched obesity cohort favored GLP-1 receptor agonist users, and the authors interpreted these data as suggesting a potentially meaningful long-term association between GLP-1 receptor agonist exposure and improved outcomes in this group

This leads to reduced blood sugar levels after meals and an increased feeling of fullness, which can aid in weight management