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Market Restraints Gastrointestinal Adverse Effects and Stringent Regulatory Requirements Restrain Market Expansion GLP-1 receptor agonists are associated with gastrointestinal side effects such as nausea, vomiting, diarrhea, and reduced appetite, particularly during treatment initiation and dose escalation

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You have a known allergy to the medication or any of its ingredients
They also promote macrophage polarization from the proinflammatory M1 phenotype to the anti-inflammatory M2 phenotype (Figure 2)

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