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However, in the studies that reported the use of a specific medication, the most frequently used SGLT2i was dapagliflozin (10/54), followed by empagliflozin (5/54) and canagliflozin (5/54) and the most frequently used GLP1-RA was exenatide (10/54) followed by semaglutide (6/54) and liraglutide (5/54)

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Macrophages can polarize into two distinct phenotypes: M1, which exhibits pro-inflammatory properties, and M2, which is associated with anti-inflammatory functions (Zhang et al., 2023

The Rationale for Dual Targeting The concept of dual GIP/GLP-1 receptor agonism emerged from observations that patients with type 2 diabetes often exhibit reduced GIP sensitivity, while GLP-1 responses may remain relatively preserved

Lipase inhibitors This drug class mainly refers to orlistat, known under the brand names Xenical and Alli
