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doi:10.36849/JDD.6550 Samantha Ouellette BA, Giulia Frias BA, Radhika Shah MD PharmD, Mahin Alamgir MD, Cindy Wassef MD Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Somerset, NJ Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic agents that work by inducing insulin secretion and inhibiting release of glucagon in a glucose-dependent manner

By age group, the 35-54 segment held 35.52% share in 2025, while the 18-34 segment is projected to grow at 15.25% CAGR through 2031

Potential signals have already emerged in the case of GLP-1 mimetic therapy, one is pancreatitis (1214) and another, which is currently confined to rodents studies, is thyroid cancer (11)

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The RCTs focused on metformin, sulfonylureas, thiazolidinedione, DPP-4 inhibitors, SGLT-2 inhibitors, alpha-glucosidase inhibitors, GLP-1 agonists, and insulin