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However, medication choices for people who are frail or who have multiple comorbidities may require modification for safety and tolerability

Read more: Common and serious side effects of Wegovy In 2026, the out-of-pocket cost for Wegovy often depends on your insurance coverage and the specific dose you need

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This adjustment period usually resolves within 24 weeks as cardiovascular fitness improves with the new body composition

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These topical approaches can be used alongside systemic medications or as standalone treatments for localized allodynia