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Specifically, neuropeptide Y/agouti-related protein (NPY/AgRP) neurons control appetite by the orexigenic effect47), and pro-opiomelanocortin/cocaine- and amphetamine-regulated transcript (POMC/CART) neurons are sensitive to peripheral hormones such as insulin and leptin by anorexigenic effects48)

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Hunger between meals may be less intense

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2.4 Study outcomes The primary outcome was the estimation of mean changes in body composition, paying particular attention to Fat Mass (FM) and Fat Free Mass (FFM), from T0 to T3 and T6