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Based on the standard reconstitution of 5mg semaglutide in 2ml bacteriostatic water, creating a 2.5mg/ml concentration

The MHRA has issued specific guidance on this risk, including the following dose limits: Maximum 20 mg per day in adults Maximum 10 mg per day in older adults and those with hepatic impairment Hydroxyzine is also subject to MHRA dose restrictions (maximum 100 mg per day in adults

Treatment requires baseline investigations and monitoring every 36 months

Semaglutide primarily targets GLP-1 receptors

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