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[DOI] [PubMed] [Google Scholar] 72.Gastaldelli A., Cusi K., Land L.F., Bray R., Brouwers B., Rodrguez

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Novo Nordisk, the maker of Ozempic and Wegovy, said drugs in this class have been used safely for years to treat diabetes and obesity

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The synthesis of orforglipron involves the assembly of three principal building blocks (the tetrahydropyran, indazole, and phenyl fragments) through sequential coupling reactions, followed by purification using standard crystallization and recrystallization techniques rather than expensive chromatographic methods