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Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the KrasG12D mouse model

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GLP-1 stimulates insulin secretion, suppresses glucagon release, and slows gastric emptying, which collectively help lower blood glucose levels and reduce appetite

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Stop Mounjaro immediately if severe, persistent abdominal pain radiating to the back with nausea and vomiting occurs