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This distribution means that while the average result is impressive, individual results vary widely

Coverage can vary widely depending on an individuals employer, plan type, and state regulations

Regulators are looking the other way

It has, in clinical comparisons, outperformed older options like Saxenda (liraglutide daily injections) which produce ~57% weight loss, and even edged out semaglutide (Wegovy)

The case for creatine on a GLP-1 is the same as the baseline case for creatine in any training population

Appetite suppression is often strongest in the first part of the day, and many patients tell me they're simply not hungry which creates a real risk of under-eating protein and starting the day in a deficit they don't recover from by dinner