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For anxiety and depression that co-occur with diabetes and obesity, semaglutide and, to a lesser extent, liraglutide might be useful dually effective therapeutic options, the authors concluded

Diabetic Retinopathy Complications in Patients with Type 2 Diabetes In a 2-year trial with semaglutide 0.5 mg and 1 mg once-weekly injection in adult patients with type 2 diabetes and high CV risk, diabetic retinopathy complications (which was a 4-component adjudicated endpoint) occurred in patients treated with semaglutide injection (3%) compared to placebo (1.8%)

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Advantages, disadvantages of using semaglutide and challenges and future research priorities Semaglutide effectively reduces glycated hemoglobin (HbA1c) levels and body weight across a broad spectrum of patients with type 2 diabetes, while also demonstrating cardiovascular safety [92]

These trials, involving thousands of participants over extended periods, will generate the data necessary for regulatory submissions