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SGLT2 inhibitors, used in the treatment of type 2 DM, have an average half-life of 11-13 hours, so most articles suggested withholding the drug three days before any elective surgery but some articles suggested a longer withholding period based on other precipitating factors contributing to euglycemic DKA

The available evidence has prompted professional and medical societies to recommend GLP-1RAs for mitigation of the cardiovascular risk in people with type 2 diabetes
Like GLP-1 itself, semaglutide is a peptide, a molecule composed of a string of amino acids joined together

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The wild card-to-uncertainty about GLP-1 meds growth will be reimbursement: spending will continue to accelerate with upside if more widely reimbursed, IQVIA projects

Experts acknowledged an adverse effect noted by patients using glucagon-like peptide-1 receptor agonists.
