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In order to account for withdrawn subjects, it was planned to randomise 20 subjects per group (i.e

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In the pivotal SURMOUNT-1 trial, which tested tirzepatide for weight loss in 2,539 adults without diabetes, insomnia was not reported as a common or statistically significant adverse event

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And a lower dose can be appropriate for some patients without becoming a universal brain health strategy

Common side effects can include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and reduced appetite
