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This distinction matters because pulsatile GH secretion maintains receptor sensitivity, while continuous exogenous GH leads to receptor downregulation and metabolic dysfunction over time

Deijen JB, Arwert LI, Drent ML

The TMJ is located near each ear and is unique for its ability to perform both hinge and sliding motions, essential for chewing, speaking, and various jaw movements

Understanding potential adverse effects enables informed decision-making and appropriate medical monitoring

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