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Rapid weight loss also strips lean muscle, not just fat, affecting strength and metabolism, especially in older adults

At the start of treatment, the average age was 57.5 years, the mean BMI was 34.7 kg/m2, and 61% had type 2 diabetes

doi:10.3389/fpubh.2022.996179 8

These small shifts generally fall within the flexibility that semaglutide tolerates without compromising steady-state concentrations

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