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Discusssion Cortisol, one of the most important human glucocorticoids, is a powerful modulator of physiological systems, including the central nervous system

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Updated cholesterol guidelines released yesterday by the American Heart Association and American College of Cardiology aim to prevent more heart attacks and strokes than ever

Although GLP-1RAs can reduce body weight by 15%25% in controlled settings, real-world adherence is limited, and nearly 70% of patients experience weight regain after discontinuation, raising the risk of long-term pharmacological dependence ( Looking ahead, the future of GLP-1based therapy will depend on addressing safety concerns, improving long-term adherence, and expanding clinical indications

Patients with severe gastrointestinal disease , including gastroparesis, may experience symptom exacerbation due to delayed gastric emptying
