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21,22 They cloned and sequenced the preproglucagon gene, discovering GLP-1 and GLP-2 hormones
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The primary outcome was percentage total weight loss, with safety among secondary outcomes

BMI measurements are counted at the start of GLP-1 therapy, so even people who fall below the threshold now can qualify if they can show they had a high enough BMI when they began taking the drugs

Br J Pharmacol Chemother

Boland et al
