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Description
In patients with type 2 diabetes already on an oral hypoglycemic agent, exenatide 10 g twice daily produced almost twice the amount of weight loss afforded by the 5 g twice daily dose, a finding that was subsequently reproduced, though not quite at the same magnitude, by other groups [54, 55,56]

This dual mechanism drives its strong efficacy for weight loss (up to 22.5% body weight [1] reduction in the SURMOUNT-1 trial [1] ) and blood sugar control

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The attendees debated where all these new treatments might fit in, especially with Eli Lilly currently dominating the market for shots and impressing attendees with data from its experimental triple-acting drug retatrutide that produced the most weight loss seen yet

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doi:10.1016/j.celrep.2020.108271 7
