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The maximum recommended dose is 70 mg per day

The biggest pros for McCullar are: It gives you the confidence that you can lose weight It makes weight loss easy Mary Frances McCullar spends less money on food, which helps her afford the cost of semaglutide

But as researchers at Yale have pointed out, patients pursuing unvalidated microdosing protocols are essentially serving as their own test subjects on both efficacy and safety

Yusta B, Matthews D, Flock GB, Ussher JR, Lavoie B, Mawe GM, Drucker DJ (2017) Glucagon-like peptide-2 promotes gallbladder refilling via a TGR5-independent, GLP-2R-dependent pathway

Pathol Biol (Paris), 40:332-337

A paper that reports that lesion of a PVN descending pathway induces obesity