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Making Informed Decisions About Your Care If you have thyroid conditions or concerns about thyroid health, you can still consider GLP-1 therapy when medically appropriate

While semaglutide offers many benefits, it also slows down the digestive process, leading to symptoms like nausea, bloating, and constipation

A miscalculation of even 10-20% can mean the difference between a therapeutic dose and a dose that triggers unnecessary side effects or provides inadequate results

According to the Summary of Product Characteristics (SmPC) approved by the MHRA, Rybelsus tablets should be kept in the original blister pack to protect them from moisture and should not be removed until just before use

In severe cases, surgical removal of the gallbladder, known as cholecystectomy, may be necessary

Once the primary visceral (intra-abdominal) fat depots are saturated, free fatty acid spillover into non-adipose tissues and begin to accumulate in ectopic fat depots (liver, skeletal muscle, heart, pancreas, kidney, bone marrow, and central nervous system (CNS) which leads to lipotoxicity, inflammation, and ultimately B-cell dysfunction [64,65,66,67,68,69,70,71]