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The combination of metformin and a GLP-1 agonist is a common pairing in type 2 diabetes management, reflecting the polypharmacy strategy I described earlier: two different mechanisms, two different targets, and lower doses of each

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Holly Wyatt, profesora adjunta asociada en Medicina en la Universidad de Colorado Anschutz

GLP-1 therapy slows gastric motility, which can reduce intrinsic factor productiona protein needed to absorb B12 from food

None of these mechanisms overlap
