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May 1 Product: Boehringer Ingelheims Cyltezo Indication: Rheumatoid arthritis, Crohns disease, ulcerative colitis and more Theres another new biosimilar option to AbbVies blockbuster antirheumatic Humira

124,125,126 The design concept of these multi-agonists is to simultaneously regulate multiple key metabolic pathways to achieve more effective control over blood sugar, body weight, and overall metabolic health

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Evidence also suggests antidepressant effects of GLP-1RAs

Regulation of cell death protease caspase-9 by phosphorylation

Recommendations have shifted from routine medication cessation to continuation with individualised risk assessment [9, 10]
