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Phase 2 trial results suggest retatrutide may offer a triple therapy option to address the multiple metabolic factors that affect people who are obese, regardless of type 2 diabetes status, said Arun J

Their pleiotropic benefits arise from intricate signalling cascades that regulate appetite, insulin secretion, and energy homeostasis across multiple tissues.

Ph 2 datathat showed weight loss of between 9.4% and 14.7% after 36 weeks on the drug compared to 2.3% for the placebo group and is currently in Ph 3