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This research provides a strong biological rationale for combining HRT and GLP-1 medications clinically

Researchers know where the receptors are, what they do when activated, and why that matters for addictive behavior

subsequently confirmed this association in a large multicenter database study of 37.1 million adults, but the incidence was low at 14.5 per 100,000 person-years among semaglutide users, and there was only a modest increase in risk attributable to semaglutide (90)

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