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Efficacy and safety data were obtained from the STEP 1 trial (body mass index [BMI], systolic blood pressure and glycaemic status), involving a cohort of adults with an average age of 46 years and obesity (BMI30 kg/m2)

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Once-weekly semaglutide 2.4 mg conferred a greater reduction in major adverse cardiovascular events than placebo, regardless of change in body weight, according to an analysis of the SELECT trial published in The Lancet