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Description
It works by stimulating insulin secretion, which helps lower blood sugar when glucose levels are high

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Mastaitis, J.W., et al., GDF8 and activin A blockade protects against GLP-1-induced muscle loss while enhancing fat loss in obese male mice and non-human primates

GLP-1 medications work by activating the glucagon like peptide-1 receptor , which slows digestion in the small intestine and helps control appetite
All patients prescribed an SGLT-2 inhibitor should be cautioned on the possibility of euglycaemic ketoacidosis, a rare complication that may occur if patients are fasting or have an intercurrent illness

JAMA 318: 14601470, 2017
