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V., Koh G

When appetite falls, food volume decreases

Generative algorithms to create new peptide variants

doi:10.1177/20420188251406456.
Following 6 weeks of HFD, all mice were switched to HFD supplemented with tamoxifen to induce cell GLP-1R knockdown and were maintained on this diet throughout study, resulting in a total duration of 8 weeks of HFD feeding before intervention, which results in impaired glucose tolerance, insulin secretion, and islet function, as previously established (2628)
By mimicking this hormone, GLP-1 helps slow down digestion, reduce hunger, and increase feelings of fullness, making it easier to eat less and lose weight
