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The magnitude of the benefits of GLP-1RA and SGLT-2 inhibitors on MACE are similar, ranging from 12 to 14% reduction of risk, but only GLP-1RA may reduce the risk of stroke

There is strong evidence to support the use of GLP-1 agonists in overweight or obese patients who have cardiovascular disease, impaired renal function or are at high risk of hypoglycaemia

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Primary cultured lung fibroblasts treated with TGF-1 combined with IL-1 (TGF-1+IL-1) were used to explore the specific effects of liraglutide, MCC950, and 3PO on fibroblast activation in vitro