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Although liraglutide is the most studied GLP-1 agonist in psychiatric patients and is available in a generic form, it requires daily dosing and is less effective than the branded, once-weekly GLP-1 agonists semaglutide and tirzepatide.

The temporal relationship between dose escalation and headache occurrence supports the hypothesis that these symptoms relate to the body's adaptation to pharmacological GLP-1 receptor stimulation

Transplantation and maintenance of hearts in the OCS set-up was performed by S.Q

[DOI] [PubMed] [Google Scholar] 150.Arterburn D.E., Telem D.A., Kushner R.F., Courcoulas A.P

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These mechanisms, whilst requiring further validation in large-scale clinical trials, provide compelling biological plausibility for the observational findings described above