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Consult your healthcare provider for medical advice

Dose splitting Some providers recommend splitting the weekly dose into two smaller injections given 3 to 4 days apart

Here is what the evidence suggests for getting the most out of every injection

Depending on your health history, your provider may order periodic lab work to check blood sugar, kidney and liver function, lipid profile, and pancreatic enzymes

Stories from users who hit plateaus and overcame them Media reports on real-world use show a pattern: people who stay on treatment and reach appropriate maintenance doses tend to see better average results than those who stop early or remain on lower doses for long periods

According to a 2024 study , people with type 2 diabetes who switched from semaglutide to tirzepatide lost even more weight over three months