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Most follow either a temporary deferral (312 months post-discontinuation) or permanent deferral depending on GLP-1 type and local regulations

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Long-term evidence, including data from landmark investigations such as the Swedish Obese Subjects (SOS) study and the Surgical Treatment and Medications Potentially Eradicate Diabetes Efficiently (STAMPEDE) trial, highlights the superior durability of surgical outcomes for both weight loss and cardiometabolic risk mitigation [32,33]

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Follow these steps as a general guide and always refer to the instructions provided with your pen: Wash your hands thoroughly before handling the pen or needle Check that the Semaglutide solution appears clear and colorless before injecting Attach a new needle to the pen for each injection Dial to the dose prescribed by your doctor Choose an injection site on the abdomen, thigh, or upper arm Rotate sites weekly to prevent tissue buildup at any single spot Inject once weekly, on the same day each week Dispose of used needles in an approved sharps container immediately after use Practical tip: Set a recurring weekly calendar reminder on your phone
