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Against this backdrop, pharmaceutical innovation has become not merely an opportunity but a necessity

doi: 10.1016/j.molmet.2021.101351 13 WenJSyedBNadoraDHow-VolkmanCBernsteinETruongAet al

Researchers at Olio Labs combined Truvetas real-world electronic health record (EHR) data, pre-clinical rodent models, and single-cell RNA sequencing to explore sex-based differences in GLP-1 drug tolerability

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doi: 10.1172/JCI25483

Interestingly, these neurons were deactivated during consumption, comparable with the activation of DMH GLP-1R neurons during consumption to encode pre-ingestive satiation [48,61]