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By early 2025, nearly 25% of diabetes patients had started a GLP1 therapy, up from just 3% four years ago

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Additionally, Retatrutide reflects the future direction of weight loss medications, multiple pathways, or hormone-based optimal solutions

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Safety and efficacy of weekly pemvidutide versus placebo for metabolic dysfunction-associated steatohepatitis (IMPACT): 24-week results from a multicentre, randomised, double-blind, phase 2b study

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and Volpe et al

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Bottom Line Despite some dizzying progress for this class of drugs, there are still so many unknowns (besides lack of explainability as already touched on)

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J Nephrol 33 , 965975 (2020)

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