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By early 2025, nearly 25% of diabetes patients had started a GLP1 therapy, up from just 3% four years ago

Additionally, Retatrutide reflects the future direction of weight loss medications, multiple pathways, or hormone-based optimal solutions

Safety and efficacy of weekly pemvidutide versus placebo for metabolic dysfunction-associated steatohepatitis (IMPACT): 24-week results from a multicentre, randomised, double-blind, phase 2b study

and Volpe et al

Bottom Line Despite some dizzying progress for this class of drugs, there are still so many unknowns (besides lack of explainability as already touched on)

J Nephrol 33 , 965975 (2020)
