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human risk is uncertain but the medications are contraindicated with personal or family history of medullary thyroid carcinoma

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These elements could be contributing to the high mortality rates and disabilities seen in those with diabetes (33)

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Exendin-4 demonstrated a GLP-1R-mediated reduction in ICP in a rodent model of hydrocephalus by inhibiting Na + - and K + -dependent adenosine triphosphatase activity in the choroid plexus [97]