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They both slow digestion, affect appetite centers in the brain, and improve glucose metabolism
Semaglutide and tirzepatide both support medical weight loss
In one tirzepatide trial for obesity, participants lost up to 20.9% of their body weight in 72 weeks with those on a higher tirzepatide dosage losing the most

How often should doses be adjusted

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Eating quickly can have a similar effect, as it gives the stomach less time to signal fullness