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Liraglutide 3 mg (Saxenda, FDA-approved for weight management), an earlier-generation daily GLP-1 injection, demonstrates similar gastrointestinal side effect patterns with diarrhea reported in approximately 21% of patients according to its FDA label

In many cases, adjustments to dosing or additional support can make treatment tolerable

Liraglutide reduces hunger cravings and suppresses appetite , which helps patients avoid over-eating

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After the 56-week treatment period, BMI standard deviation scores (BMI SDS) decreased by a mean of 0.23 in the liraglutide group, with no change in the placebo group

This is fundamentally different from prescription GLP-1 medications that directly activate GLP-1 receptors