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Description
The glucose-dependency of GLP-1s insulinotropic effect it only amplifies insulin secretion when blood glucose is elevated is a key pharmacological property that distinguishes GLP-1 from non-incretin insulin secretagogues in research models

GLP-1 increases preingestive satiation via hypothalamic circuits in mice and humans
A slower rate of weight loss is the most effective way to prevent a gaunt appearance

It can cause learning difficulties, low self-esteem, social problems, and an increased risk of substance abuse, including smoking

When you lose weight rapidly, its not just fat that you shed

5h, i, it appears that after using the closed-loop patch, although the blood glucose level rose above the normal range (blue and red curves in Fig
