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Based on the strength of evidence and safety boundaries, a more rational clinical positioning is to reserve GLP-1RAs as an individualized tool for intensive metabolic optimization prior to ART in refractory PCOS individuals with high BMI and prior weight-loss failure

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doi: 10.1073/pnas.1415675112 49 ChiouHCLinMWHsiaoPJChenCLChiaoSLinTYet al