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So the most fair interpretation is not, Berberine is useless. The fair interpretation is: Berberine may produce modest metabolic effects, but its weight-loss effect is nowhere near the effect seen with GLP-1-based obesity medications
You need proper medical supervision: baseline labs, regular monitoring, specialist involvement when indicated, multidisciplinary care coordination

Calcium, iron, vitamin D, omega-3 fatty acids, and B vitamins all flow from mother to infant through milk

When following any intense weight loss program, people should be aware that mental health issues, disordered eating, or eating disorder symptoms may be triggered

Chatterton H, Younger T, Fischer A, Khunti K (2012) Risk identification and interventions to prevent type 2 diabetes in adults at high risk: summary of NICE guidance
