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Description

Human islets contain a subpopulation of glucagon-like peptide-1 secreting alpha cells that is increased in type 2 diabetes

Systematic monitoring of protein consumption helps ensure adequacy during Wegovy treatment, allowing timely adjustments to prevent muscle loss and optimise treatment outcomes

Tirzepatide SURMOUNT-1 (72 Weeks, 2,539 Participants) The SURMOUNT-1 trial was larger and longer than the Retatrutide Phase 2 study

The tirzepatide dose groups and regimens were as follows: 12 mg (4 mg for weeks 0-3, 8 mg for weeks 4-7, and 12 mg for weeks 8-11), 15 mg-1 (2.5 mg for weeks 0-1, 5 mg for weeks 2-3, 10 mg for weeks 4-7, and 15 mg for weeks 8-11), and 15 mg-2 (2.5 mg for weeks 0-3, 7.5 mg for weeks 4-7, and 15 mg for weeks 8-11)

Ultimately, this switch might be suitable for those who are seeking more substantial weight loss and improved glycemic control, particularly if previous treatments have been insufficient