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More recently, it has received approval for use as an anti-obesity medication, marketed under the brand name Wegovy

Wet your hands Apply soap Rub your hands together for at least 20 seconds, making sure to include the backs of your hands, between your fingers, and under your nails Rinse with clean, running water Dry thoroughly Consider medication

Orforglipron's signaling profile has been characterized in the peer-reviewed publication in Science Translational Medicine in 2024, which reported that orforglipron demonstrates a Gs-biased signaling profile with relatively reduced beta-arrestin recruitment compared to peptide agonists

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doi: 10.1111/dom.14725 [DOI] [PMC free article] [PubMed] [Google Scholar] Associated Data This section collects any data citations, data availability statements, or supplementary materials included in this article.