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Approved for Obesity: Wegovy (semaglutide ) : Approved specifically for chronic weight management in adults with obesity or overweight conditions, alongside dietary and exercise changes

Wednesdays approval is backed by data from two Phase III studiesBE HEARD I and BE HEARD II

In 2021, the FDA approved semaglutide for chronic weight management in adults with obesity or overweight under the name Wegovy (Novo Nordisk) [29]

Characterization of binding sites for oxyntomodulin on a somatostatin-secreting cell line (RIN T3) Endocrinology

INTERVENTIONS THAT MAY AFFECT GUT MICROBIOTA PROMOTE GUT PEPTIDE SECRETION, SUCH AS GLP-1 Oral antidiabetic drugs promoted the GLP-1 secretion In addition to dietary factors, nonantibiotic drugs also affect the microbiota composition and function

another method tried was addition of polyethylene glycol (PEG) to form PEGylated GLP-1