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in people without diabetes) and Have Diabetes (SYNCHRONISE-2

Patients with chronic intestinal pathology are candidates for GLP-1 RA use

These typically include: Erythema (redness) at the injection site Pruritus (itching) localised to the area Swelling or induration (hardening of tissue) Mild pain or tenderness Bruising (ecchymosis) in some cases These reactions usually appear within hours to days following injection and typically resolve spontaneously within 25 days without specific intervention

Florida Weight Loss Clinic and Telehealth Compliance Guide (2025) (Updated 2025) MedicalDirector Co

These studies collectively highlight the roles of glucagon-like peptide-1 receptor agonists in promoting weight loss and reducing appetite through central and peripheral mechanisms. 3

Managing Side Effects: To minimize side effects, patients should eat something before taking the medication, stay hydrated, and avoid large meals right after taking the medication