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For women with PCOS or other underlying hormonal conditions , continued monitoring and possible adjustment of concurrent treatments (such as metformin or hormonal contraceptives) may be necessary

The FDA has not approved any GLP-1 weight loss patches yet because of the skin-penetration challenge

If these mechanisms translate consistently into humans, this could reshape how we think about patient selection and treatment goalsespecially in individuals who may not achieve substantial weight reduction but still derive meaningful hepatic benefit

But that shouldnt be surprising

GLP-1 is crucial for maintaining glucose homeostasis and has become a target for obesity and diabetes treatments

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