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My 100-pound weight loss was slow (happening over 3-4 years), but even still, I struggled with many of these: Self-sabotage I wanted to lose weight, yet I was afraid of being in the spotlight

moreover it is still unclear whether GIP has direct, insulin independent, metabolic effects on adipose tissue

24 These effects result from several interrelated mechanisms, including improvements in insulin sensitivity, reductions in sympathetic activity, decreased plasma volume, and favorable changes in vascular function, many of which overlap with the direct pathways described above

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