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Gastrointestinal side effects like diarrhea affect up to 20% of semaglutide users during the first weeks of treatment

Conclusions Consistent with clinical trials, real-world tirzepatide treatment was associated with greater 6-month weight reduction and more frequent achievement of weight-reduction targets and improvements in select cardiometabolic parameters than semaglutide among adults with obesity without diabetes

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Yes, but with important precautions

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